Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri
Abstract Background The opportunistic pathogen Naegleria fowleri establishes infection in the human brain, killing almost invariably within 2 weeks.The amoeba performs piece-meal ingestion, or trogocytosis, of brain material causing direct tissue damage and massive inflammation.The cellular basis distinguishing N.fowleri from other Naegleria specie